We’re all used to using inline S-Controls, dragging and dropping them into page layouts. And the entire Salesforce community has been spending tons of time recreating page layouts in Visualforce, just to edit one small piece of a page.
As an example, how would you implement the example at developer.force.com: Visualforce Dynamic Edit Page? You would do it the way it was explained in the blog post!
Well the rules of the game have changed.
As long as you use a Standard Controller, you can now place Visualforce pages IN regular page layouts!
Inline Visualforce Page Layout screenshot
The article was written by Sati Hillyear, who is also an expert on the License Manager Application. Check it out!
[Addendum 5-9-2009: For another example of this, see Jeff Douglas’ blog post.]